LIVER EXTRACT REFRACTORY MEGALOBLASTIC ANEMIA

Liver extract refractory megaloblastic anemia.

ECENTLY we have had the opportunity to study a patient with a macrocytic anemia and megaloblastic bone marrow, who was refractory to parenteral therapy with vitamin B,2 and refined liver extract, but who responded to folic acid. This type of macrocytic anemia is rare, particularly in this country. Observations made in this case support the concept of a chemical interrelationship between liver e...

Refractory megaloblastic anemia.

Refractory pancytopenia and megaloblastic anemia due to falciparum malaria.

Anemia is a common complication in malarial infection. Direct destruction and ineffective erythropoesis does not adequately explain the cause of anemia in malaria. We present a case with refractory megaloblastic anemia with asymptomatic falciparum malaria. We hypothesize that promoter variants in the inducible nitric oxide synthase gene might be the cause of severe refractory megaloblastic anem...

Refractory megaloblastic anemia associated with excretion of orotic acid.

By CiIAnLI s M. HUGULEY, Jn., JAMES A. BAIN, SHIRLEY L. RIVERS AND ROBERT B. ScoGcINs T HE MAJORITY of anemias associated with a megalohiastic hone marrow respond to vitamin B,2 parenterally. Those which do not respond usually fall into well defined categories of nutritional deficiency, intestinal malahsorption syndromes, pernicious anemia of pregnancy, megaloblastic anemia of infancy or reacti...

Megaloblastic Anemia in Pregnancy

MegalobJastic Anemia in Pregnancy Megaloblastic Anemia is one of The Rather Common Diseases of Pregnant Women Caused by Folic acid Defi­ciency The Disease Might Be Hazardous To affected Mo­thers and also Could be Fatal for foetus too.  Megaloblastic Pregnant Women Will have Signs and Symptoms of This Disease mostly after 29th. Week of pregnancy.  Adequate amount of Folate Will prevent Compli...